Pig by DK Publishing

By DK Publishing

A photographic paperback sequence designed to introduce the interesting global of animals and the way they increase. during this informative and hugely visible sequence, attractive step by step images permits young children to determine a butterfly emerge from its cocoon and unfold its wings, or see what occurs whilst an egg hatches and a chick emerges. every one publication comes with a decal sheet jam-packed with lovely photos of the animals featured within the ebook.

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T C = BALB/c origin. t B = C57BL/6 origin. 3. Analysis of traits dependent on replicative observations. Genetics of certain traits (for example, virus resistance) is difficult to determine on segregating populations because more than one mouse of the same genotype is required for measurement of such traits. The RI strains, in which a selected number of F 2 segregants can be replicated at will, may circumvent this difficulty. 4. Detection of linkage. If a new gene shows the same SDP as a gene already known, the two genes may be linked.

Green and Doolittle 1963, Snell and Bunker 1965, E. Green 1966), the simplest of which is the NX backcross system. The principle of the NX system is explained in Fig. 2-4, using as an example strains B 10 (background strain) and A (donor strain). A congenic line begins with a crossing of the two strains and backcrossing of the (BlOxA)F 1(= NI) hybrid to the background strain. The resulting N2 generation is typed with BIO anti-A (H-2 b anti-H-r) antiserum, the negative animals (H-2 b/H-2 b) are discarded, and the positive animals (H-2"/ H-2Q) are backcrossed again to the background strain.

Taylor et al. 1973). However, even the lines that meet the criterion do not provide absolute assurance that all differences have been eliminated. Currently available CR lines differing in the B-2 complex are listed in Table 2-8; a complete list of all mouse CR lines can be found elsewhere (Klein 1973b). Table 2-8. C-H-2b. CA(MS06) B10. A(SR) (Continued) 37 The Mouse and Its Forms Table 2-8. S(8R) iaI j ja k m mI 01 02 p pa q r s sqI sq2 tI t2 t3 14 It v wI w2 w3 w4 w5 w6 yI y2 ? C. Recombinant Inbred (RI) Strains "RI strains are those which have been derived from the cross of two unrelated but highly inbred progenitor strains and which have been maintained independently under a regimen of strict inbreeding since the F 2 generation" (Bailey 1971).

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