Category: Biostatistics

Angewandte Statistik: Methodensammlung mit R by Jürgen Hedderich, Lothar Sachs

By Jürgen Hedderich, Lothar Sachs

Das Standardwerk für statistische Methoden in den Biowissenschaften und der Medizin. Der "Hedderich/Sachs" erläutert statistische Ansätze und gibt dem Anwender anschaulich und zugleich praxisnah alle notwendigen Methoden an die Hand, um Daten zu gewinnen, zu analysieren und zu beurteilen. Neben Hinweisen und Empfehlungen zur Planung und Auswertung von Studiendaten ermöglichen zahlreiche Beispiele und Querverweise sowie ein umfangreiches Sach- und Literaturverzeichnis einen breit gefächerten Zugang zur Statistik. Entscheidungsdiagramme sowie zusätzliche Verzeichnisse der Übersichten, Abbildungen und Tabellen erleichtern die Orientierung bei der Auswahl und Anwendung statistischer Verfahren. Neben einer schlanken Einführung in das Statistikprogramm R, enthält das Buch für viele Beispiele die entsprechenden Programm-Codes, welche schnell Rechnungen zur Kontrolle sowie mit eigenen Daten ermöglichen. Insbesondere für die 15. Auflage wurde das Buch umfassend bearbeitet. Es enthält zahlreiche Präzisierungen, neu aufgenommene Ansätze mit Beispielen sowie weiterführende Ergänzungen.

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Analyzing rater agreement by Alexander von Eye

By Alexander von Eye

Contract between raters is of serious value in lots of domain names. for instance, in medication, diagnoses are frequently supplied by means of multiple physician to ensure the proposed remedy is perfect. In legal trials, sentencing relies, between different issues, at the whole contract one of the jurors. In observational experiences, researchers bring up reliability by way of studying discrepant scores. This ebook is meant to aid researchers statistically research rater contract through reviewing 4 assorted ways to the technique.The first method introduces readers to calculating coefficients that permit one to summarize agreements in one rating. the second one strategy includes estimating log-linear versions that let one to check particular hypotheses concerning the constitution of a cross-classification of 2 or extra raters' judgments. The 3rd procedure explores cross-classifications or raters' contract for signs of contract or war of words, and for symptoms of such features as traits. The fourth technique compares the correlation or covariation buildings of variables that raters use to explain items, behaviors, or participants. those constructions will be in comparison for 2 or extra raters. All of those equipment function on the point of saw variables.This ebook is meant as a reference for researchers and practitioners who describe and overview items and behaviour in a couple of fields, together with the social and behavioral sciences, facts, drugs, company, and schooling. It additionally serves as an invaluable textual content for graduate-level equipment or review sessions present in departments of psychology, schooling, epidemiology, biostatistics, public well-being, verbal exchange, advertising, and sociology. publicity to regression research and log-linear modeling is useful.

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Integrated Microsystems: Electronics, Photonics, and by Krzysztof Iniewski

By Krzysztof Iniewski

As speedy technological advancements take place in electronics, photonics, mechanics, chemistry, and biology, the call for for transportable, light-weight built-in microsystems is relentless. those units have become exponentially smaller, more and more utilized in every little thing from games, listening to aids, and pacemakers to extra complicated biomedical engineering and armed forces functions. Edited by means of Kris Iniewski, a innovative within the box of complex semiconductor fabrics, built-in Microsystems: Electronics, Photonics, and Biotechnology specializes in ideas for optimized layout and fabrication of those clever miniaturized units and structures. Composed of contributions from specialists in academia and world wide, this reference covers methods appropriate with CMOS built-in circuits, which mix computation, communications, sensing, and actuation functions. mild on math and physics, with a better emphasis on microsystem layout and configuration and electric engineering, this booklet is geared up in 3 sections—Microelectronics and Biosystems, Photonics and Imaging, and Biotechnology and MEMs. It addresses key issues, together with actual and chemical sensing, imaging, shrewdpermanent actuation, and knowledge fusion and administration. utilizing tables, figures, and equations to aid illustrate options, participants research and clarify the potential for rising functions for parts together with biology, nanotechnology, micro-electromechanical platforms (MEMS), microfluidics, and photonics.

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Converting Data into Evidence: A Statistics Primer for the by Alfred DeMaris

By Alfred DeMaris

Converting facts into facts: A records Primer for the scientific Practitioner offers an intensive advent to the most important statistical thoughts that scientific practitioners come across throughout their expert careers. those recommendations play an incredible half in evidence-based medication or EBM. Adherence to EBM calls for clinical practitioners to maintain abreast of the result of scientific study as pronounced of their basic and strong point journals. on the center of this study is the technology of data. it truly is via statistical concepts that researchers may be able to figure the styles within the facts that inform a medical tale worthy reporting. The authors begin through discussing samples and populations, concerns desirous about causality and causal inference, and methods of describing info. They then proceed throughout the significant inferential recommendations of speculation trying out and estimation, delivering examples of univariate and bivariate assessments. The assurance then strikes to statistical modeling, together with linear and logistic regression and survival research. In a last chapter, a trouble-free advent to a few more recent, state-of-the-art, regression ideas may be integrated, such as fixed-effects regression and growth-curve modeling. a special function of the paintings is the huge presentation of statistical purposes from fresh clinical literature. Over 30 varied articles are explicated herein, taken from such journals. because of this primer, the clinical researcher also will locate it more uncomplicated to speak with the statisticians on his or her study crew. The ebook features a word list of statistical phrases for simple entry. this is often an incredible reference paintings for the cabinets of physicians, nurses, nurse practitioners, physician’s assistants, clinical scholars, and residents. 

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Régression: Théorie et applications (Statistique et by Éric Matzner-Løber

By Éric Matzner-Løber

Cet ouvrage disclose de manière détaillée, exemples à l'appui, l’une des méthodes statistiques les plus courantes : los angeles régression. Les premiers chapitres sont consacrés à los angeles régression linéaire uncomplicated et a number of. Ils expliquent les fondements de l. a. méthode, tant au niveau des choix opérés que des hypothèses et de leur utilité. Ensuite sont développés les outils permettant de vérifier les hypothèses de base mises en œuvre par l. a. régression. Une présentation basic des modèles d'analyse de los angeles covariance et de l. a. variance est effectuée. Enfin, les derniers chapitres sont consacrés au choix de modèles ainsi qu'à certaines extensions de l. a. régression: lasso, PLS, PCR... l. a. présentation témoigne d'un réel souci pédagogique des auteurs qui bénéficient d'une expérience d'enseignement auprès de publics très variés. Les résultats exposés sont replacés dans l. a. standpoint de leur utilité pratique grâce à l'analyse d'exemples concrets. Les commandes permettant le traitement des exemples sous le logiciel R figurent dans le corps du texte. Enfin chaque chapitre est complété par une suite d'exercices corrigés. Le niveau mathématique requis le rend available aux étudiants des écoles d'ingénieurs, de Masters et aux chercheurs dans les divers domaines des sciences appliquées.

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Applied Functional Data Analysis by J.O. Ramsay

By J.O. Ramsay

A pleasant, if overpriced, e-book, yet now not one who you want to hold, not like Ramsay and Silverman's "Functional facts research" (FDA). AFDA elaborates numerous examples brought in FDA. The examples hide approximately 60% of FDA's fabric: smoothing is given less area than in FDA, and regression (cf. FDA's Chapters 12-15) is passed over. while you are picking out among the 2 books, opt for FDA.

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Missing Data in Longitudinal Studies: Strategies for by Michael J. Daniels, Joseph W. Hogan

By Michael J. Daniels, Joseph W. Hogan

Drawing from the authors’ personal paintings and from the newest advancements within the box, lacking info in Longitudinal reviews: suggestions for Bayesian Modeling and Sensitivity research describes a accomplished Bayesian technique for drawing inference from incomplete information in longitudinal reviews. to demonstrate those equipment, the authors hire a number of info units all through that disguise various examine designs, variable varieties, and lacking facts matters. The publication first experiences sleek techniques to formulate and interpret regression types for longitudinal facts. It then discusses key principles in Bayesian inference, together with specifying earlier distributions, computing posterior distribution, and assessing version healthy. The booklet conscientiously describes the assumptions had to make inferences a few full-data distribution from incompletely saw information. For settings with ignorable dropout, it emphasizes the significance of covariance types for inference in regards to the suggest whereas for nonignorable dropout, the booklet stories numerous types intimately. It concludes with 3 case stories that spotlight very important positive factors of the Bayesian method for dealing with nonignorable missingness. With feedback for extra interpreting on the finish of so much chapters in addition to many purposes to the overall healthiness sciences, this source bargains a unified Bayesian method of deal with lacking info in longitudinal reports.

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A Mathematical Approach to Multilevel, Multiscale Health by Rodrick Wallace

By Rodrick Wallace

This e-book, in line with released reviews, takes a distinct point of view at the 30-year cave in of pharmaceutical productiveness within the look for small molecule "magic bullet" interventions. The relentless escalation of inflation-adjusted expense consistent with authorized drugs within the usa -- from $200 million in 1950 to $1.2 billion in 2010 -- has pushed giants to, at most sensible, slavish imitation in drug layout, and at worst, abandonment of analysis and embracing of frequent fraud in customer advertising and marketing.

The booklet adapts formalism throughout a couple of disciplines to the tactic for layout of mutilevel interventions, focusing first on molecular, mobile, and bigger scale examples, after which extending the argument to the simplifications supplied by way of the dominant position of social and cultural buildings and approaches in person and inhabitants styles of health and wellbeing and disorder.

instead of "magic bullets", we needs to now follow "magic innovations" that act throughout either the dimensions and point of association. This e-book presents an introductory roadmap to the recent instruments that would be wanted for the layout of such options.

Readership: Undergraduate, graduate, researchers and pros in biomathematics, biostatistics, mathematical modeling, complicated platforms and prescribed drugs.

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