Advances in Statistical Bioinformatics: Models and by Do K.-A., Qin Z.S., Vannucci M. (eds.)

By Do K.-A., Qin Z.S., Vannucci M. (eds.)

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Extra info for Advances in Statistical Bioinformatics: Models and Integrative Inference for High-Throughput Data

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As with public databases, programmers have made available a large number of software packages that can process sequence data in different ways. The first priority for interpreting sequencing data is to assemble the short read lengths and align them to a reference genome. Among the NCBI’s many tools is BLAST (basic local alignment search tool), which is widely used to map similarities between sequences. MAQ is a similar tool developed for use with the Illumina/Solexa instrument. The goal of programmers in creating these software packages is to increase accuracy and decrease run time.

Genet. , 5, 309–314. Das, P. , and Singal, R. 2004. DNA methylation and cancer. J. Clin. , 22, 4632–4642. Dassie, J. , Liu, X. , Thomas, G. , et al. 2009. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nat. , 27, 839–849. , Montero, M. , et al. 2009. Specific gene hypomethylation and cancer: new insights into coding region feature trends. Bioinformation, 3, 340–343. Elbashir, S. , et al. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells.

PIs are then responsible for keeping any data they access secure. Data that cannot potentially identify an individual are publicly available. 1. This page displays the cancer types with available data, including the number of patients with samples, the number of samples for which data are available for download, and the date when the downloadable data were last updated. 3). jsp displaying the cancer types with available data, including the number of patients with samples, the number of samples for which data are available for download, and the date the downloadable data were last updated.

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